Pathology of bone marrow in human herpes virus-8 (HHV8)-associated multicentric Castleman disease
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چکیده
منابع مشابه
Plasma HHV8 DNA predicts relapse in individuals with HIV-associated multicentric Castleman disease.
HIV-associated multicentric Castleman disease (HIV-MCD) is a rare lymphoproliferative disorder caused by infection with human herpesvirus-8. The disease follows a relapsing and remitting clinical course, with marked systemic symptoms during an active attack, which can prove fatal. Its incidence is rising, and new data indicate the utility of the anti-CD20 monoclonal antibody rituximab at induci...
متن کاملBone marrow findings in HIV-positive patients with Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.
Kaposi sarcoma herpesvirus (KSHV), also known as human herpesvirus-8, is associated with 1 form of multicentric Castleman disease (MCD) and is the etiologic agent for most MCD in human immunodeficiency virus (HIV)-infected patients. Diagnosis is usually determined by lymph node biopsy. Bone marrow findings in KSHV-MCD are not well characterized. We conducted histomorphologic and immunohistochem...
متن کاملInitial human herpesvirus-8 rash and multicentric Castleman disease.
We describe a human immunodeficiency virus-infected man with relapsing rashes and reactivation of human herpesvirus-8 (HHV-8) infection, which evolved into multicentric Castleman disease. Initial skin biopsy revealed infiltrating HHV-8-positive plasmablasts, a subset of which supported lytic infection. We document the first case, to our knowledge, of HHV-8-induced rash and suggest that circulat...
متن کاملComplete remission in a patient with human herpes virus-8 negative multicentric Castleman disease using CHOP chemotherapy.
Multicentric Castleman disease (MCD) is a rare lymphoproliferative disorder. Although MCD pathogenesis is unclear, studies have suggested that human herpesvirus 8 (HHV-8) may be associated with the disorder. Recent reports have identified MCD cases without viral infection. A 43-year-old woman presented to our hospital for fever and myalgia of 6 months' duration. The complete blood count reveale...
متن کاملAssociated Multicentric Castleman ' s Disease − Human Herpesvirus 8 Infection in Patients With POEMS Syndrome
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2004
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2004.05230.x